Kristin Grussmayer
Joined:
I am an assistant professor at the Department of Bionanoscience, TU Delft and the Kavli Institute of Nanoscience Delft. I studied Physics at Heidelberg University with a specialization in Biophysics. As the Heidelberg-Cornell fellow and with support from the Fulbright program, I spent a year at Cornell University. I carried out my Diploma and doctoral thesis work in the Institute for Physical Chemistry & CellNetworks Cluster of Excellence at the BioQuant Center in Heidelberg; during my doctoral studies I was as a fellow of the DFG graduate college GRK 1114. I worked on transcription factor DNA biosensors and established a method for counting molecules based on photon statistics for quantification in biological systems and material science. After my PhD in Physics (summa cum laude), I moved to Switzerland for a postdoc at the École Polytechnique Fédérale de Lausanne (EPFL). As a Horizon 2020 Marie Sklodowska-Curie fellow, I became an expert in multiplane super-resolution and quantitative phase imaging and collaborated with neurobiologists. Since 2021, I lead an independent research group at TU Delft. My lab develops microscopy and analysis tools, establishes new classes of fluorescence probes, and applies them to address relevant questions in molecular and cell biology.
Research themes with our lab
Smart microscopy
Labelfree & quantitative phase imaging
Multiplane
Neurodegeneration
Publications with our group (see more on Google Scholar)
| Mapping volumes to planes: Camera-based strategies for snapshot volumetric microscopy Moritz Engelhardt, Kristin Grussmayer Published in Frontiers in Physics, October 2022 (see publication) |
| SOLEIL: single-objective lens inclined light sheet localization microscopy Shih-Te Hung, Jelmer Cnossen, Daniel Fan, Marijn Siemons, Daphne Jurriens, Kristin Grussmayer, Oleg Soloviev, Lukas C. Kapitein, and Carlas S. Smith Published in Biomedical Optics Express, August 2022 (see publication) |
| Parameter-free image resolution estimation based on decorrelation analysis Adrien Descloux, Kristin Grussmayer, ALexandra Radenovic Published in Nature Methods, August 2019 (see publication) |
| Combined multi-plane phase retrieval and super-resolution optical fluctuation imaging for 4D cell microscopy Adrien Descloux, Kristin Grussmayer, E. Bostan, T. Lukes, A. Bouwens, A. Sharipov1, S. Geissbuehler, A.-L. Mahul-Mellier, H. A. Lashuel, M. Leutenegger and T. Lasser Published in Nature Methods, February 2018 (see publication) |